Drug Standards
Apexbio Technology LLC Granisetron HCl 107007-99-8 100mg
Granisetron HCl (CAS 107007-99-8) is a selective antagonist of the serotonin 5-hydroxytryptamine type 3 (5-HT sub 3 /sub ) receptor By competitively inhibiting 5-HT sub 3 /sub receptor-mediated signaling Granisetron HCl suppresses serotonin-induced activation of the vomiting reflex pathway in both central and peripheral nervous systems This pharmacological activity underlies its utility in preventing and investigating the mechanisms of chemotherapy-induced and postoperative nausea and vomiting Granisetron HCl is widely employed in preclinical and clinical studies to elucidate 5-HT sub 3 /sub receptor function and to explore antiemetic strategies
TARGETMOL CHEMICALS INC SALMETEROL XINAFOATE 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Salmeterol Xinafoate (GR 33343X xinafoate) is a long-acting (beta)2-adrenergic receptor agonist with anti-inflammatory effects used in the treatment of asthma symptoms and chronic obstructive pulmonary disease (COPD) symptoms. purity: 98%
Medchemexpress LLC Raloxifene (hydrochloride) | 82640-04-8 | 99.8% | 510.04 | 1 ML
Raloxifene hydrochloride is a second-generation selective and orally active estrogen receptor modulator. It exhibits estrogen-agonistic effects on bone and lipid metabolism and estrogen-antagonistic effects on uterine endometrium and breast tissue.
- Estrogen-agonistic effects on bone and lipid metabolism
- Estrogen-antagonistic effects on uterine endometrium and breast tissue
- For research use only
- Purity of 99.8%
- Stable under recommended storage conditions
Apexbio Technology LLC Norfloxacin hydrochloride 104142-93-0 10mg
Norfloxacin hydrochloride is a small-molecule inhibitor targeting bacterial DNA gyrase It is designed to inhibit DNA gyrase an enzyme essential for the supercoiling and replication of bacterial DNA thereby disrupting bacterial DNA synthesis and interfering with bacterial replication and growth Norfloxacin hydrochloride exerts its biological activity primarily through the inhibition of DNA gyrase by binding within the enzyme s active site impeding its catalytic activity Based on these pharmacological properties Norfloxacin hydrochloride holds research potential in the study of bacterial resistance mechanisms bacterial enzyme inhibition assays antimicrobial susceptibility testing and therapeutic research on antibacterial treatment strategies against Gram-positive and Gram-negative bacteria
Medchemexpress LLC Ketorolac (Standard) | 74103-06-3 | 5 MG
Ketorolac (Standard) is the analytical standard for Ketorolac, designed for research and analytical applications. It functions as a non-steroidal anti-inflammatory drug (NSAID) and is a nonselective COX inhibitor.
- Functions as a nonselective COX inhibitor with IC50 values of 20 nM for COX-1 and 120 nM for COX-2.
- Used as a 0.5% ophthalmic solution for researching allergic conjunctivitis, cystoid macular edema, intraoperative miosis, and postoperative ocular inflammation and pain.
- Identified as a DDX3 inhibitor with potential for cancer research.
![Medchemexpress LLC 1H-Benzimidazole, 6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1) | 161796-78-7 | MFCD00870347 | 99.4% | 367.40 | 5 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000384294-logo.png-250.jpg){kind=logo}
Medchemexpress LLC 1H-Benzimidazole, 6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1) | 161796-78-7 | MFCD00870347 | 99.4% | 367.40 | 5 MG
Esomeprazole sodium is a potent and orally active proton pump inhibitor. It reduces acid secretion by inhibiting the H+, K+-ATPase in gastric parietal cells. Additionally, it acts as an exosome inhibitor by blocking exosome release through the inhibition of V-H+-ATPases. It has potential for research related to symptomatic gastroesophageal reflux disease and for suppressing the growth of triple-negative breast cancer cells.
- Potent and orally active proton pump inhibitor
- Reduces acid secretion
- Acts as an exosome inhibitor
- Potential for symptomatic gastroesophageal reflux disease research
- For research use only
Sigma Aldrich Fine Chemicals Biosciences 5-Amino-2,4,6-triiodo-N-methylisophthalamic acid United States Pharmacopeia (USP) Reference Standard | 2280-89-9 | 50MG
5-Amino-2,4,6-triiodo-N-methylisophthalamic acid United States Pharmacopeia (USP) Reference Standard | Mol Wt: 571.88 | 2280-89-9 | 50MG
Cayman Chemical D-a-Tocopheryl QuInon 250mg
An oxidative metabolite of vitamin E; has antioxidant activity in ORAC and radical trapping assays at 25 µM; inhibits (1S,3R)-RSL3-induced ferroptosis in Q7 cells (EC50 = 0.233 µM); decreases serum MDA and blood glucose levels and restores the number and diversity of intestinal microflora in a rat model of high cholesterol and cholate diet-induced NASH at 20 mg/kg
Medchemexpress LLC Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-11-hydroxy-6-methyl-17-(1-oxopropoxy) | 86401-95-8 | MFCD00866150 | 98.9% | 472.57 g/mol | C27H36O7 | 10 MG
Methylprednisolone aceponate is a research-grade glucocorticoid analytical standard used as a reference material in analytical and biochemical assays. It is intended for laboratory research use only and is commonly used for method development and quantitation by HPLC, GC, and mass spectrometry. CAS 86401-95-8; molecular formula C27H36O7; molecular weight 472.57 g/mol.
- Research-grade analytical standard suitable for HPLC, GC, and MS
- Acts as a selective glucocorticoid receptor ligand for anti-inflammatory studies
- High reported purity (98.9% by LCMS)
- Available in small-mass sizes for use as calibration and reference material
- For research use only; not intended for human or clinical use
Medchemexpress LLC Nomegestrol acetate | 58652-20-3 | MFCD00941390 | 99.7% | 370.48 g/mol | C23H30O4 | 50 MG
Nomegestrol acetate is an orally active, highly selective progestogen and progesterone receptor full agonist supplied for research use. It is provided as a solid for preclinical and in vitro endocrine and receptor pharmacology studies.
- Orally active, highly selective progestogen.
- Progesterone receptor full agonist useful for receptor pharmacology.
- High purity suitable for analytical and preclinical studies.
- Solid, white to off-white appearance for stable handling and storage.
- Available in multiple sizes for flexible experimental scale.
- Defined storage conditions to maintain compound stability.
Medchemexpress LLC 2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carbonitrile | 1240948-72-4 | MFCD28404592 | 1g
Vonoprazan impurity 6 is an impurity of Vonoprazan (HY-100007)
Sigma Aldrich Fine Chemicals Biosciences Clozapine | 5786-21-0 | MFCD00153785 | 100MG
Clozapine | Mol Wt: 326.82 | 5786-21-0 | MFCD00153785 | 100MG
Selleck Chemical LLC Enoxaparin sodium S5415-25mg
Enoxaparin sodium(PK 10169) is a low-molecular-weight heparin used to prevent and treat deep vein thrombosis or pulmonary embolism It binds to and accelerates the activity of antithrombin III
Echelon Biosciences Research Labs Ins(1,2,6)P3 100 ug
Inositol phosphates are important signaling molecules involved in numerous cellular functions. Inositol 1,2,6-trisphosphate (Ins(1,2,6)P3), or trinositol, is an analog of Ins(1,4,5)P3 which inhibits inflammatory reactions, inhibits edema formation in skin burns, inhibits vasoconstriction by neropeptide Y (NPY), and treats acute nerve function abnormalities in diabetes. This item is non returnable
Apexbio Technology LLC Citalopram hydrobromide 59729-32-7 10mM (in 1mL DMSO)
Citalopram hydrobromide (CAS 59729-32-7) is a selective serotonin reuptake inhibitor (SSRI) that functions by specifically blocking the reuptake of 5-hydroxytryptamine (5-HT) at presynaptic neuronal membranes thereby increasing 5-HT concentrations in the synaptic cleft In vitro studies demonstrate that citalopram hydrobromide exhibits potent nanomolar-level inhibition of 5-HT reuptake in synaptosomal preparations as well as low nanomolar inhibition in rabbit platelet assays This compound is widely utilized in research exploring serotonergic signaling neurotransmission processes and experimental models of depression